A Guide to Understanding and Interpreting the DUTCH Test Panel for Healthcare Providers
What is the DUTCH Test?

The DUTCH (Dried Urine Test for Comprehensive Hormones) test is a comprehensive hormone panel that provides a detailed overview of a patient’s sex and adrenal hormones, including their metabolites. It also measures cortisol patterns, melatonin, and organic acids. The test is often used by healthcare providers to gain insights into the hormonal status of patients dealing with issues like adrenal fatigue, menstrual cycle irregularities, and hormone-related symptoms.
How to Use This Guide
This guide serves as a framework for healthcare providers to interpret DUTCH test results, identify potential causes of hormonal imbalances, and suggest tailored treatments. The guide will walk you through assessing symptoms, abnormal lab results, potential root causes, and possible treatments.
Step-by-Step Approach to Interpreting DUTCH Test Results
- Identify Patient’s Symptoms of Hormonal Dysfunction
- Begin by noting the symptoms the patient is experiencing, which may suggest an underlying hormonal imbalance. For example, symptoms such as depression, insomnia, and fatigue can indicate cortisol dysregulation.
- Explore Alternative Causes of Symptoms
- While hormonal dysfunction may explain the symptoms, it’s important to rule out other potential causes. For instance, depression and insomnia could also result from thyroid issues, blood sugar dysregulation, or low progesterone levels.
- Evaluate Lab Results for Abnormal Levels
- Use the DUTCH Complete™ or DUTCH Plus® to assess specific hormone levels and patterns. For example, high cortisol levels could suggest that the HPA (hypothalamic-pituitary-adrenal) axis is overactive, leading to conditions like adrenal fatigue.
- Determine Root Causes of Abnormal Lab Results
- Before jumping to treatment, explore the possible root causes of abnormal hormone levels. High cortisol, for example, might be caused by acute inflammation, hyperthyroidism, or chronic pain, rather than simply being a result of stress.
- Select Potential Treatments Based on Abnormalities
- Once the root causes are identified, appropriate treatments can be considered. These may include lifestyle changes, supplements, meditation, or adaptogens to balance high cortisol, for example. It’s critical to address root causes such as stress or inflammation before prescribing treatments.
- Choose Specific Supplements or Products
- Precision Analytical, the company behind DUTCH, offers supplement guides tailored to the results of the test. These guides help in selecting high-quality products from functional medicine brands to support treatment.
Hormone Family Breakdown
Cortisol and Stress Hormones
Cortisol is a key hormone released by the adrenal glands and plays a role in regulating blood sugar, metabolism, inflammation, and stress response. Abnormal cortisol levels can manifest in a variety of symptoms:
- High Cortisol: Symptoms may include anxiety, insomnia, weight gain (especially around the abdomen), and high blood pressure. It can be caused by chronic stress, inflammation, and thyroid issues.
- Low Cortisol: Symptoms may include fatigue, burnout, dizziness, and low mood. Low cortisol can result from long-term stress or adrenal insufficiency.
Common Causes of Abnormal Cortisol Levels
- High Cortisol: Inflammation, chronic pain, hyperthyroidism, and sleep dysregulation.
- Low Cortisol: Chronic stress, adrenal insufficiency, or autoimmune diseases like Addison’s disease.
Treatment Options for Cortisol Imbalances
- For High Cortisol: Adaptogens such as ashwagandha and rhodiola, lifestyle modifications, meditation, and reducing sources of inflammation.
- For Low Cortisol: Adaptogenic herbs, stress management, and, in rare cases, cortisol replacement therapy.
Sex Hormones: Estrogen, Progesterone, and Testosterone
- Progesterone and Estrogen
- In women, progesterone and estrogen regulate the menstrual cycle and reproductive health. Imbalances can cause symptoms such as mood swings, hot flashes, and irregular periods.
- Low Progesterone: Symptoms include insomnia, anxiety, and irregular cycles. Causes may include poor ovulation or ovarian insufficiency.
- High Estrogen: Symptoms like weight gain, bloating, and breast tenderness often accompany elevated estrogen, possibly caused by poor liver detoxification or environmental estrogen exposure.
- Testosterone
- Testosterone plays a vital role in both men and women, influencing libido, muscle mass, and energy levels.
- Low Testosterone in Women: Leads to fatigue, low libido, and muscle weakness, which may be caused by adrenal insufficiency or aging.
- High Testosterone in Women: May cause acne, facial hair growth, and hair thinning, often linked to polycystic ovary syndrome (PCOS) or insulin resistance.
Treatment Considerations for Sex Hormones
- Progesterone Support: Supplements such as Vitex or progesterone creams can be used to balance low progesterone.
- Estrogen Metabolism: Support liver detox pathways using DIM (diindolylmethane) and ensure a healthy diet rich in fiber to enhance estrogen clearance.
- Testosterone: For low testosterone, supplements like DHEA or tribulus may be helpful. In cases of high testosterone, reducing insulin resistance and blocking 5-alpha reductase can alleviate symptoms.
General Considerations for Hormonal Treatment
In every case of hormone dysfunction, it’s essential to address foundational aspects of health:
- Lifestyle Factors: Diet, exercise, sleep, and stress management must be optimized for any treatment plan to be effective.
- Other Tests: Consider running additional lab tests, including thyroid function, CBC (complete blood count), CMP (comprehensive metabolic panel), and vitamin D levels to gain a full picture of the patient’s health.
Supplementation and Product Recommendations
Precision Analytical offers detailed guides for choosing supplements that match the patient’s hormonal profile. These include adaptogens for stress management, vitamins and minerals to support detoxification, and other functional medicine products. For more specific guidance, contact the company or explore their online resources.
Conclusion
The DUTCH test is a powerful tool for healthcare providers to assess and treat hormone imbalances. By following the structured approach outlined in this guide—identifying symptoms, assessing lab results, finding root causes, and choosing appropriate treatments—practitioners can offer personalized and effective hormone support for their patients.
Healthmatters.io is the ideal platform for both practitioners and individuals looking to take control of their health by understanding and tracking lab results in one secure, organized place. For practitioners, Healthmatters.io provides an intuitive interface to interpret complex lab data with ease, offering insights that can enhance patient care. Regular users benefit from clear, easy-to-read explanations of their lab results, empowering them to make informed health decisions. With the added ability to track progress over time, Healthmatters.io becomes an invaluable tool for anyone serious about optimizing their health, all while ensuring top-notch security and privacy for sensitive data.
Medical Disclaimer:
The information provided on Healthmatters.io is for general informational purposes only. All content, including text, graphics, images, and other material contained on this website, is not intended and should not be construed as medical advice, diagnosis, or treatment.
Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
Healthmatters.io does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the site. Reliance on any information provided by Healthmatters.io, its employees, others appearing on the site at the invitation of HealthMatters.io, or other visitors to the site is solely at your own risk.
Sign up to HealthMatters.io today as a practitioner here: https://healthmatters.io/plans/healthmatters-pro
Sign up to HealthMatters.io today as a personal user: https://healthmatters.io/plans/personal
If you think you may have a medical emergency, call your doctor, go to the emergency department, or call 911 immediately.
