Biomarkers

High Triglycerides: Causes, Risks, and How to Lower Them

Triglycerides are a key marker on a cholesterol test and an important indicator of metabolic and cardiovascular health. If your triglyceride levels are elevated, it can signal insulin resistance, inflammation, or increased heart disease risk. The good news is that triglycerides often respond quickly to lifestyle changes once the underlying causes are addressed.

This guide explains what triglycerides are, what high levels mean, and how to lower them safely and effectively.

For a full overview of how triglycerides fit into your cholesterol profile, see our complete guide to the lipid panel:
https://healthmatters.io/biomarker-categories/lipid-panel


What are triglycerides?

Triglycerides are a type of fat found in the blood. After you eat, your body converts excess calories — especially from carbohydrates and sugar — into triglycerides for storage. These fats are later used for energy between meals.

Triglycerides are measured as part of a standard cholesterol test and are included in a lipid panel along with LDL, HDL, and total cholesterol:
https://healthmatters.io/biomarker-categories/lipid-panel

While triglycerides are essential for energy balance, chronically elevated levels can increase the risk of cardiovascular disease and metabolic disorders.


Triglyceride levels: what is considered normal?

Triglyceride LevelInterpretation
Under 100 mg/dLOptimal
100–149Borderline
150–199Elevated
200–499High
500+Very high

Levels above 150 mg/dL are generally considered elevated and may increase cardiovascular risk, especially when combined with low HDL or high LDL.


What causes high triglycerides?

High triglycerides are often linked to metabolic health rather than dietary fat intake alone.

Common causes include:

  • High sugar or refined carbohydrate intake
  • Insulin resistance
  • Weight gain or obesity
  • Alcohol consumption
  • Physical inactivity
  • Poor sleep
  • Chronic stress
  • Diabetes or prediabetes
  • Hypothyroidism
  • Certain medications
  • Genetic factors

Many people with elevated triglycerides also have low HDL and signs of metabolic syndrome.


Why high triglycerides matter

Elevated triglycerides are associated with:

  • Increased cardiovascular risk
  • Insulin resistance
  • Fatty liver disease
  • Inflammation
  • Higher risk of type 2 diabetes

Very high triglycerides (typically above 500 mg/dL) can also increase the risk of pancreatitis, a serious condition involving inflammation of the pancreas.

Triglycerides should always be interpreted alongside other markers in a lipid panel:
https://healthmatters.io/biomarker-categories/lipid-panel


How triglycerides fit into the bigger picture

Triglycerides rarely act alone. Patterns across the lipid panel provide important clues.

High triglycerides + low HDL

Often associated with insulin resistance or metabolic syndrome.

High triglycerides + high LDL

May increase cardiovascular risk and signal metabolic imbalance.

High triglycerides + normal LDL

Can still indicate metabolic dysfunction even if LDL appears acceptable.

Looking at triglycerides in context helps guide the right interventions.


How to lower triglycerides

Triglycerides often respond quickly to targeted lifestyle changes.

Reduce sugar and refined carbohydrates

Excess sugar is one of the strongest drivers of elevated triglycerides. Reducing added sugar and refined grains can significantly lower levels.

Improve insulin sensitivity

Regular exercise and balanced meals can help regulate blood sugar and reduce triglyceride production.

Increase physical activity

Aerobic exercise and resistance training can lower triglycerides and improve overall lipid balance.

Limit alcohol

Alcohol can significantly raise triglycerides in some individuals, even at moderate intake levels.

Focus on whole foods

A diet rich in fiber, vegetables, healthy fats, and protein can help stabilize triglycerides and improve metabolic health.

Omega-3 fatty acids

Omega-3s from fatty fish or supplements may help lower triglycerides in some individuals.


When medication may be considered

If triglycerides remain significantly elevated despite lifestyle changes, clinicians may consider medication or targeted therapies. Treatment decisions depend on overall cardiovascular risk and other lipid markers.


When to recheck triglycerides

Repeat testing is often recommended:

  • After dietary or lifestyle changes
  • Every 3–12 months if elevated
  • When monitoring treatment
  • As part of routine preventive care

Tracking trends over time provides more insight than a single measurement.


Common questions

Are triglycerides 200 high?

Triglycerides around 200 mg/dL are considered high and may increase cardiovascular risk. Lifestyle changes can often improve levels.

Are triglycerides 150 bad?

Levels around 150 mg/dL are borderline elevated and may signal metabolic imbalance.

Can triglycerides be lowered quickly?

Yes. Reducing sugar intake, increasing physical activity, and improving metabolic health can lower triglycerides within weeks.

Do triglycerides increase heart disease risk?

Elevated triglycerides are associated with increased cardiovascular risk, especially when combined with low HDL or high LDL.


The bottom line

High triglycerides are common and often reflect underlying metabolic health. The good news is that they are highly responsive to lifestyle changes, particularly improvements in diet, exercise, and insulin sensitivity.

Understanding triglyceride levels in the context of your full cholesterol profile can help guide prevention strategies and reduce long-term cardiovascular risk. For a complete breakdown of cholesterol and triglyceride markers together, visit our full lipid panel guide:
https://healthmatters.io/biomarker-categories/lipid-panel

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