Pentadecanoic acid is an odd numbered fatty acid with a 15-carbon backbone (15:0) and widely considered as one biomarker to assess dairy consumption/intake. It is not normally synthesized by humans, but is found in trace amounts in dairy products (milk fat) and ruminant meat fat.
Higher values:
– When measuring fatty acids in whole plasma (not erythrocytes), increased levels of pentadecanoic acid correlate to a more than twofold higher risk of coronary heart disease.
–Â Pentadecanoic acid is positively correlated with total dairy intake.
– As a possible way to lower penntadecanoic acid level one can reduce overall dairy intake as part of a healthy diet that is rich in fruits, vegetables, and whole grains, but low in sodium, red meats, dairy, sugar sweetened beverages and trans fats.
– Pentadecanoic acid can accumulate in a vitamin B12 deficiency.
References:
– https://www.ncbi.nlm.nih.gov/pubmed/25647578
– https://www.ahajournals.org/doi/10.1161/JAHA.113.000393
– https://www.ncbi.nlm.nih.gov/pubmed/14518600?dopt=Abstract
– https://www.ncbi.nlm.nih.gov/pubmed/7644455?dopt=Abstract
– https://www.ncbi.nlm.nih.gov/pubmed/17921367?dopt=Abstract
– https://www.ncbi.nlm.nih.gov/pubmed/22585901?dopt=Abstract
– https://www.ncbi.nlm.nih.gov/pubmed/20089734?dopt=Abstract
– https://www.ncbi.nlm.nih.gov/pubmed/21068345?dopt=Abstract
– https://www.ncbi.nlm.nih.gov/pubmed/21660519?dopt=Abstract
– https://www.ncbi.nlm.nih.gov/pubmed/9925119?dopt=Abstract
– https://www.ncbi.nlm.nih.gov/pubmed/23466047?dopt=Abstract
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