What is Citrate?

Citrate, cis-Aconitate, and Isocitrate are involved in:

  • energy production and
  • removal of toxic ammonia.

The energy pathways in your cells require citrate, α-ketoglutarate, and succinate, which are formed from essential amino acids.

High levels:

High levels can indicate ammonia toxicity. Chronic loss of these valuable compounds can contribute to loss of organ reserve and disturbances in neurological function. If they are low they can indicate a need for essential amino acids, especially arginine.

Low levels:

Low levels of citrate, α-ketoglutarate, and succinate may indicate amino acid imbalances that can affect your energy pathways.



The information on is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

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