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Biomarkers

What is Mead (from Genova test)?

mead acid genova high low meaning deficiency essential fatty acids treatment

Mead acid is an omega9 fatty acid.

mead acid genova high low meaning deficiency essential fatty acids treatment
Mead acid is an omega-9 fatty acid. Its elevated presence in the blood is an indication of essential fatty acid deficiency

Mead Acid (plasma) is a marker for overall, essential fatty acid status. It is produced in human tissues from oleic acid and, therefore, is not considered essential. The essential fatty acids, linoleic and alpha linolenic, prevent Mead acid formation in individuals with good dietary fat intake. When essential fatty acids are depleted, higher levels of Mead acid are detected. During essential fatty acid deficiency, Mead acid serves as a structural component in cell membranes as a substitute for the normal polyunsaturated fatty acids derived from essential precursors. It cannot substitute, however, in the critical role of precursor to eicosanoid cell regulators. Mead acid formulation may also be stimulated by high intake of omega 3 fatty acids.

Its elevated presence in the blood is an indication of essential fatty acid deficiency.

in the absence of adequate ALA and LA, oleic acid is metabolized to mead acid

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