Veillonella are anaerobic, gram-negative cocci, part of the normal flora of the mouth, gastrointestinal tract, and vaginal tract.
They are a normal bacterium in the intestines and oral mucosa of mammals. In humans they have been rarely implicated in cases of osteomyelitis and endocarditis, for example with the species Veillonella parvula.
Higher levels:
– Imbalances noted in IBS, although findings are mixed: some studies reported higher concentrations in IBS, in IBS-C, IBS-D; others have reported lower counts or lower counts weakly correlating with greater symptom severity.
– Veillonella have been found in atherosclerotic (cardiovascular) plaques, fecal samples, and oral washing from subjects with known cardiac events. These observations suggest an association between Veillonella and cholesterol.
Lower levels:
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Lower levels of Veillonella have been found in people who fall on the severe end of the autistic spectrum.
References:
– Veillonella montpellierensis Endocarditis [L]
– Cross sectional evaluation of the gut-microbiome metabolome axis in an Italian cohort of IBD patients [L]
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