Biomarkers

What is Beta defensin 2? High and low values | Lab results explained

Beta defensin 2 is an antibiotic peptide locally regulated by inflammation in humans. It is produced by a number of epithelial cells and exhibits potent antimicrobial activity against Gram-negative bacteria and Candida, but not Gram-positive bacteria. It has been speculated that beta-defensin 2 may contribute to the infrequency of Gram-negative infections on skin and lung tissue.

References:

Elevated Human [beta]-Defensin-2 Levels Indicate an Activation of the Innate Immune System in Patients With Irritable Bowel Syndrome
Langhorst, Jost; Junge, Angela; Rueffer, Andreas; Wehkamp, Jan; Foell, Dirk; et al. The American Journal of Gastroenterology; New York Vol. 104, Iss. 2,  (Feb 2009): 404-410. [L]

WHAT DOES IT MEAN IF YOUR BETA DEFENSIN 2 RESULT IS TOO HIGH?

Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome. [L] Consider broad spectrum probiotics to improve gut diversity along with probiotic foods.

Disclaimer:

Test results may vary depending on your age, gender, health history, the method used for the test, and other things. Your test results may not mean you have a problem. Ask your healthcare provider what your test results mean for you. 

The information on healthmatters.io is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

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