Lysine is found in great quantities in muscle tissues, stimulates calcium absorption, carnitine synthesis, and growth and repair of muscle tissue. In diabetics, it can increase insulin sensitivity and decrease blood sugar levels. Excessive supplementation can add to the total-body nitrogen load, challenging ammonia clearance and leading to kidney problems.
Low lysine levels may be caused by prolonged stress, too much arginine or histidine supplementation competing for absorption, or carnitine deficiency. Muscle weakness,
fatigue, or high serum triglycerides due to decreased fatty acid transport may result from low levels of carnitine and lysine.
Low levels can inhibit transamination of AA collagen synthesis.
Possible treatment: Carnitine
Although rare, high levels may be due to lysine supplementation or impaired metabolism of lysine. Add vitamin C, niacin, vitamin B6, α-ketoglutarate and iron to enhance utilization of lysine.
- Vitamin C
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